When we think about metabolic health, we often focus on body weight, blood glucose, cholesterol, blood pressure and body fat. But there is another important piece of the metabolic picture that we sometimes overlook - our muscles. Skeletal muscle is not simply the tissue that enables us to walk, lift, climb stairs and carry shopping. It is also a major metabolic organ. Muscle stores glucose as glycogen, uses large amounts of glucose and fatty acids for energy, responds to ins

If you’ve ever lost weight successfully—only to hit a plateau or regain it—you’re not alone. Most people who lose weight struggle to maintain it, and, over time, the weight often returns. This frustrating experience is not about will power; it is usually driven by a real biological process called metabolic adaptation. Metabolic adaptation refers to the body’s ability to reduce energy expenditure in response to calorie restriction. This adaptation evolved as a survival mecha